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Detailed information for vg0700431655:

Variant ID: vg0700431655 (JBrowse)	Variation Type: SNP
Chromosome: chr07	Position: 431655
Reference Allele: C	Alternative Allele: T
Primary Allele: T	Secondary Allele: C

Inferred Ancestral Allele : T (evidence from allele frequency in Oryza rufipogon: T: 1.00, others allele: 0.00, population size: 291. )

Flanking Sequence (100 bp) in Reference Genome:

TTGTCATGGCCTGCAGTGAACTATTGCAATGAATTATTGGACAAATATCTGGCGTTTGGCACTTGTACCATGGAGGGAGCTATGGTTGGCTTTGGACCGA[C/T]
ACTACTATCATACTAGTAGTTTGGGTGTCATGAGCTGACATGAAAGTTCCTGACGATTCCAATTTAGTACATGAAATTACTTTGTGATATCCTGAAATCC

Reverse complement sequence

GGATTTCAGGATATCACAAAGTAATTTCATGTACTAAATTGGAATCGTCAGGAACTTTCATGTCAGCTCATGACACCCAAACTACTAGTATGATAGTAGT[G/A]
TCGGTCCAAAGCCAACCATAGCTCCCTCCATGGTACAAGTGCCAAACGCCAGATATTTGTCCAATAATTCATTGCAATAGTTCACTGCAGGCCATGACAA

Allele Frequencies:

Populations	Population Size	Frequency of T(primary allele)	Frequency of C(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	55.60%	44.00%	0.04%	0.32%	NA
All Indica	2759	83.80%	15.70%	0.04%	0.43%	NA
All Japonica	1512	0.70%	99.30%	0.00%	0.07%	NA
Aus	269	97.40%	2.60%	0.00%	0.00%	NA
Indica I	595	98.00%	1.70%	0.00%	0.34%	NA
Indica II	465	41.50%	57.60%	0.00%	0.86%	NA
Indica III	913	94.30%	5.50%	0.11%	0.11%	NA
Indica Intermediate	786	85.90%	13.50%	0.00%	0.64%	NA
Temperate Japonica	767	0.10%	99.70%	0.00%	0.13%	NA
Tropical Japonica	504	1.60%	98.40%	0.00%	0.00%	NA
Japonica Intermediate	241	0.40%	99.60%	0.00%	0.00%	NA
VI/Aromatic	96	10.40%	89.60%	0.00%	0.00%	NA
Intermediate	90	37.80%	58.90%	1.11%	2.22%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0700431655	C -> DEL	N	N	silent_mutation	Average:4.21; most accessible tissue: Minghui63 panicle, score: 7.125	N	N	N	N
vg0700431655	C -> T	LOC_Os07g01720.1	3_prime_UTR_variant ; 381.0bp to feature; MODIFIER	silent_mutation	Average:4.21; most accessible tissue: Minghui63 panicle, score: 7.125	N	N	N	N
vg0700431655	C -> T	LOC_Os07g01730.1	upstream_gene_variant ; 429.0bp to feature; MODIFIER	silent_mutation	Average:4.21; most accessible tissue: Minghui63 panicle, score: 7.125	N	N	N	N
vg0700431655	C -> T	LOC_Os07g01710.1	downstream_gene_variant ; 3132.0bp to feature; MODIFIER	silent_mutation	Average:4.21; most accessible tissue: Minghui63 panicle, score: 7.125	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0700431655	C	T	0.01	0.01	0.01	0.0	0.01	0.01

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0700431655	NA	5.16E-10	mr1005	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	1.50E-08	mr1110	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	4.11E-06	mr1216	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	1.20E-25	mr1495	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	4.30E-06	mr1835	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	4.93E-12	mr1904	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	1.37E-06	mr1110_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	3.67E-10	mr1158_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	3.95E-11	mr1383_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	1.23E-23	mr1495_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	3.09E-08	mr1889_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0700431655	NA	6.06E-13	mr1904_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251