Search for Variation information by Variation ID:

Please input a variation ID (e.g., vg0722097923 , STR0500036000 ).

Detailed information for vg0424742530:

Variant ID: vg0424742530 (JBrowse)Variation Type: SNP
Chromosome: chr04Position: 24742530
Reference Allele: AAlternative Allele: C
Primary Allele: CSecondary Allele: A

Inferred Ancestral Allele : A (evidence from allele frequency in Oryza rufipogon: A: 0.98, C: 0.02, others allele: 0.00, population size: 119. )

Flanking Sequence (100 bp) in Reference Genome:


GTCCGACGGCACGCTGTGTGGTCCCGTCATCGACGACGCGTCGCTCGTCAGTGTCCACAGCCACCGCCGGTTCCTTCTGTAATATTATTACTATCGTCAA[A/C]
GTCACTAGAATTTAAAATGACTTAAAGTTGTCCCATATGAAGGAATATCTCAATTCCTTTTATATGATTCTTATGCCAAAAGGGTGAGATGATTTTTTTT

Reverse complement sequence

AAAAAAAATCATCTCACCCTTTTGGCATAAGAATCATATAAAAGGAATTGAGATATTCCTTCATATGGGACAACTTTAAGTCATTTTAAATTCTAGTGAC[T/G]
TTGACGATAGTAATAATATTACAGAAGGAACCGGCGGTGGCTGTGGACACTGACGAGCGACGCGTCGTCGATGACGGGACCACACAGCGTGCCGTCGGAC

Allele Frequencies:

Populations Population SizeFrequency of C(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 52.40% 46.90% 0.04% 0.61% NA
All Indica  2759 88.00% 11.20% 0.07% 0.72% NA
All Japonica  1512 0.70% 98.90% 0.00% 0.33% NA
Aus  269 3.00% 97.00% 0.00% 0.00% NA
Indica I  595 95.60% 3.20% 0.00% 1.18% NA
Indica II  465 95.50% 3.70% 0.00% 0.86% NA
Indica III  913 80.10% 19.60% 0.11% 0.22% NA
Indica Intermediate  786 86.90% 12.10% 0.13% 0.89% NA
Temperate Japonica  767 0.30% 99.60% 0.00% 0.13% NA
Tropical Japonica  504 1.60% 98.00% 0.00% 0.40% NA
Japonica Intermediate  241 0.40% 98.80% 0.00% 0.83% NA
VI/Aromatic  96 0.00% 100.00% 0.00% 0.00% NA
Intermediate  90 34.40% 61.10% 0.00% 4.44% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg0424742530 A -> C LOC_Os04g41740.1 3_prime_UTR_variant ; 19.0bp to feature; MODIFIER silent_mutation Average:89.463; most accessible tissue: Zhenshan97 panicle, score: 97.556 N N N N
vg0424742530 A -> C LOC_Os04g41730.1 upstream_gene_variant ; 4534.0bp to feature; MODIFIER silent_mutation Average:89.463; most accessible tissue: Zhenshan97 panicle, score: 97.556 N N N N
vg0424742530 A -> C LOC_Os04g41750.1 upstream_gene_variant ; 2167.0bp to feature; MODIFIER silent_mutation Average:89.463; most accessible tissue: Zhenshan97 panicle, score: 97.556 N N N N
vg0424742530 A -> C LOC_Os04g41759.1 upstream_gene_variant ; 4424.0bp to feature; MODIFIER silent_mutation Average:89.463; most accessible tissue: Zhenshan97 panicle, score: 97.556 N N N N
vg0424742530 A -> DEL N N silent_mutation Average:89.463; most accessible tissue: Zhenshan97 panicle, score: 97.556 N N N N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID Ref Alt Root (RT) Young Leaf (YL) Flag Leaf (FL) Young Panicle (YP) Lemma & Palea (LP) Stamen & Pistil (SP)
vg0424742530 A C 0.16 0.12 0.08 0.06 0.1 0.05

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg0424742530 NA 5.28E-51 mr1063 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.49E-08 mr1260 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.62E-15 mr1261 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 5.64E-12 mr1744 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 8.92E-31 mr1745 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 4.70E-17 mr1913 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.10E-11 mr1914 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 5.17E-45 mr1094_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.31E-60 mr1096_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.15E-50 mr1111_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.50E-53 mr1121_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.01E-63 mr1125_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.69E-35 mr1129_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.12E-53 mr1144_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.85E-25 mr1244_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 1.99E-20 mr1255_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.32E-27 mr1270_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.66E-16 mr1457_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 3.31E-22 mr1551_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 6.23E-08 mr1690_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 3.41E-16 mr1744_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 4.77E-41 mr1745_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 8.39E-72 mr1798_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 2.92E-32 mr1913_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0424742530 NA 8.92E-30 mr1932_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251