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Detailed information for vg1222758888:

Variant ID: vg1222758888 (JBrowse)Variation Type: SNP
Chromosome: chr12Position: 22758888
Reference Allele: CAlternative Allele: T
Primary Allele: CSecondary Allele: T

Inferred Ancestral Allele : C (evidence from allele frequency in Oryza rufipogon: C: 1.01, others allele: 0.00, population size: 236. )

Flanking Sequence (100 bp) in Reference Genome:


ATAGTTTCTACCAAGCGGCCGAAATTAATCTACGCATCACGCCGTCCGCCGCCGCTGCGAGAGTGCGACAACTCTTTGTAGGTTTGTCCTAAAAACCTTC[C/T]
GTTTTGCCCACGAGACGGGTAGTTATCCTCAAATCGATCTAAATCGGCCTAGAGGCTGATTTTGATCTCTAAATCGGCTTTGCTAGCCGGTTTAGCTGTT

Reverse complement sequence

AACAGCTAAACCGGCTAGCAAAGCCGATTTAGAGATCAAAATCAGCCTCTAGGCCGATTTAGATCGATTTGAGGATAACTACCCGTCTCGTGGGCAAAAC[G/A]
GAAGGTTTTTAGGACAAACCTACAAAGAGTTGTCGCACTCTCGCAGCGGCGGCGGACGGCGTGATGCGTAGATTAATTTCGGCCGCTTGGTAGAAACTAT

Allele Frequencies:

Populations Population SizeFrequency of C(primary allele) Frequency of T(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 83.10% 0.30% 2.20% 14.35% NA
All Indica  2759 71.50% 0.50% 3.73% 24.25% NA
All Japonica  1512 99.70% 0.10% 0.07% 0.20% NA
Aus  269 100.00% 0.00% 0.00% 0.00% NA
Indica I  595 88.40% 0.00% 1.18% 10.42% NA
Indica II  465 77.20% 1.10% 4.09% 17.63% NA
Indica III  913 54.80% 0.70% 5.15% 39.43% NA
Indica Intermediate  786 74.80% 0.40% 3.82% 20.99% NA
Temperate Japonica  767 99.70% 0.10% 0.13% 0.00% NA
Tropical Japonica  504 99.40% 0.00% 0.00% 0.60% NA
Japonica Intermediate  241 100.00% 0.00% 0.00% 0.00% NA
VI/Aromatic  96 99.00% 0.00% 0.00% 1.04% NA
Intermediate  90 94.40% 0.00% 0.00% 5.56% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg1222758888 C -> DEL N N silent_mutation Average:15.573; most accessible tissue: Minghui63 panicle, score: 29.741 N N N N
vg1222758888 C -> T LOC_Os12g37140.1 upstream_gene_variant ; 1597.0bp to feature; MODIFIER silent_mutation Average:15.573; most accessible tissue: Minghui63 panicle, score: 29.741 N N N N
vg1222758888 C -> T LOC_Os12g37130-LOC_Os12g37140 intergenic_region ; MODIFIER silent_mutation Average:15.573; most accessible tissue: Minghui63 panicle, score: 29.741 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg1222758888 8.83E-07 2.55E-07 mr1083 Ind_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1222758888 6.58E-07 6.58E-07 mr1926 Ind_All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251