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Detailed information for vg1001213195:

Variant ID: vg1001213195 (JBrowse)	Variation Type: SNP
Chromosome: chr10	Position: 1213195
Reference Allele: C	Alternative Allele: T
Primary Allele: C	Secondary Allele: T

Inferred Ancestral Allele : C (evidence from allele frequency in Oryza rufipogon: C: 1.00, T: 0.01, others allele: 0.00, population size: 236. )

Flanking Sequence (100 bp) in Reference Genome:

TCTTCTCTTTATCCTCTCTCTCATCTCTTCTCTCTATCCTCTCTCTCTAGTAGTAAGCTGGTTCATCTCATAGATGCTCTAATGGCCTCACTTACTGAGA[C/T]
GGCAGAGCGGGGCGGGCGGTGGCTGGAGTGGCGGTAGATAGAGCATGCTGGCAGAGCAGAGTGAACCATCGTCGTCAACCGCTGTCGCACCAGCCACAGC

Reverse complement sequence

GCTGTGGCTGGTGCGACAGCGGTTGACGACGATGGTTCACTCTGCTCTGCCAGCATGCTCTATCTACCGCCACTCCAGCCACCGCCCGCCCCGCTCTGCC[G/A]
TCTCAGTAAGTGAGGCCATTAGAGCATCTATGAGATGAACCAGCTTACTACTAGAGAGAGAGGATAGAGAGAAGAGATGAGAGAGAGGATAAAGAGAAGA

Allele Frequencies:

Populations	Population Size	Frequency of C(primary allele)	Frequency of T(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	60.50%	39.40%	0.11%	0.00%	NA
All Indica	2759	33.90%	66.00%	0.14%	0.00%	NA
All Japonica	1512	98.60%	1.40%	0.00%	0.00%	NA
Aus	269	99.60%	0.40%	0.00%	0.00%	NA
Indica I	595	3.70%	96.30%	0.00%	0.00%	NA
Indica II	465	39.40%	60.60%	0.00%	0.00%	NA
Indica III	913	49.80%	49.90%	0.22%	0.00%	NA
Indica Intermediate	786	34.90%	64.90%	0.25%	0.00%	NA
Temperate Japonica	767	99.20%	0.80%	0.00%	0.00%	NA
Tropical Japonica	504	97.60%	2.40%	0.00%	0.00%	NA
Japonica Intermediate	241	98.80%	1.20%	0.00%	0.00%	NA
VI/Aromatic	96	97.90%	2.10%	0.00%	0.00%	NA
Intermediate	90	80.00%	18.90%	1.11%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg1001213195	C -> T	LOC_Os10g02940.1	downstream_gene_variant ; 980.0bp to feature; MODIFIER	silent_mutation	Average:86.067; most accessible tissue: Zhenshan97 young leaf, score: 91.899	N	N	N	N
vg1001213195	C -> T	LOC_Os10g02950.1	downstream_gene_variant ; 2806.0bp to feature; MODIFIER	silent_mutation	Average:86.067; most accessible tissue: Zhenshan97 young leaf, score: 91.899	N	N	N	N
vg1001213195	C -> T	LOC_Os10g02960.1	downstream_gene_variant ; 4334.0bp to feature; MODIFIER	silent_mutation	Average:86.067; most accessible tissue: Zhenshan97 young leaf, score: 91.899	N	N	N	N
vg1001213195	C -> T	LOC_Os10g02930-LOC_Os10g02940	intergenic_region ; MODIFIER	silent_mutation	Average:86.067; most accessible tissue: Zhenshan97 young leaf, score: 91.899	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg1001213195	C	T	-0.01	-0.01	-0.01	-0.01	-0.01	-0.01

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg1001213195	3.20E-09	NA	mr1486	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	1.34E-10	6.63E-10	mr1486	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	7.61E-08	NA	mr1548	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	5.36E-08	3.03E-07	mr1548	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	5.24E-06	4.66E-06	mr1588	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	NA	1.38E-13	mr1592	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	NA	6.64E-07	mr1728	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	1.37E-10	NA	mr1486_2	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	5.80E-13	1.25E-15	mr1486_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	2.58E-07	4.91E-07	mr1588_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1001213195	NA	2.45E-12	mr1728_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251