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Detailed information for vg0819413174:

Variant ID: vg0819413174 (JBrowse)Variation Type: SNP
Chromosome: chr08Position: 19413174
Reference Allele: TAlternative Allele: A
Primary Allele: TSecondary Allele: A

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:


TTTTCTTCTTTCTTCTAAATGCGTGATGTAGCGGGAGCCACCTCCGATGACCCATGTATACCATCTTTCGTGATTTCTTCAGCCACCGGCTTCGTGTATA[T/A]
TCCTTGCAATCGGAGCATGCATTCTTTCCTTTTATAGTTTGTCCGGAAAGATTACCGAGTGCAGGGTAGTCATTAATAGTGCAGAACAATAGAACTCTTA

Reverse complement sequence

TAAGAGTTCTATTGTTCTGCACTATTAATGACTACCCTGCACTCGGTAATCTTTCCGGACAAACTATAAAAGGAAAGAATGCATGCTCCGATTGCAAGGA[A/T]
TATACACGAAGCCGGTGGCTGAAGAAATCACGAAAGATGGTATACATGGGTCATCGGAGGTGGCTCCCGCTACATCACGCATTTAGAAGAAAGAAGAAAA

Allele Frequencies:

Populations Population SizeFrequency of T(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 43.60% 0.10% 46.76% 9.56% NA
All Indica  2759 16.70% 0.10% 67.23% 15.95% NA
All Japonica  1512 83.10% 0.00% 16.47% 0.46% NA
Aus  269 74.00% 0.40% 25.65% 0.00% NA
Indica I  595 22.90% 0.20% 47.23% 29.75% NA
Indica II  465 9.70% 0.20% 64.09% 26.02% NA
Indica III  913 14.30% 0.00% 82.15% 3.50% NA
Indica Intermediate  786 19.00% 0.10% 66.92% 13.99% NA
Temperate Japonica  767 99.50% 0.00% 0.39% 0.13% NA
Tropical Japonica  504 56.00% 0.00% 43.25% 0.79% NA
Japonica Intermediate  241 87.60% 0.00% 11.62% 0.83% NA
VI/Aromatic  96 97.90% 0.00% 2.08% 0.00% NA
Intermediate  90 55.60% 0.00% 38.89% 5.56% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg0819413174 T -> A LOC_Os08g31400.1 missense_variant ; p.Glu374Asp; MODERATE nonsynonymous_codon ; E374D Average:19.099; most accessible tissue: Minghui63 young leaf, score: 33.985 benign 1.274 TOLERATED 0.81
vg0819413174 T -> DEL LOC_Os08g31400.1 N frameshift_variant Average:19.099; most accessible tissue: Minghui63 young leaf, score: 33.985 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg0819413174 4.38E-06 7.78E-07 mr1197 All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0819413174 6.60E-06 6.60E-06 mr1197 Ind_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251