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Detailed information for vg0630338357:

Variant ID: vg0630338357 (JBrowse)	Variation Type: SNP
Chromosome: chr06	Position: 30338357
Reference Allele: T	Alternative Allele: C
Primary Allele: C	Secondary Allele: T

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

TGAATAATATTTTACGTGTGACTAAATATTTTCAATTTTTTCACAAATTTTTCAAATAAGACGGACGGTCAAACGTTGGGCACAAATATCCACGGCTGTA[T/C]
TTATTTTGGAACGGAGGTAGTATTTAGAATTGAAGGTCATGGTACATGATGTATGATGATTCAGGAATAACATTATGTAAATTACTCCATTCGTTCTAAA

Reverse complement sequence

TTTAGAACGAATGGAGTAATTTACATAATGTTATTCCTGAATCATCATACATCATGTACCATGACCTTCAATTCTAAATACTACCTCCGTTCCAAAATAA[A/G]
TACAGCCGTGGATATTTGTGCCCAACGTTTGACCGTCCGTCTTATTTGAAAAATTTGTGAAAAAATTGAAAATATTTAGTCACACGTAAAATATTATTCA

Allele Frequencies:

Populations	Population Size	Frequency of C(primary allele)	Frequency of T(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	70.80%	29.20%	0.04%	0.00%	NA
All Indica	2759	98.20%	1.70%	0.04%	0.00%	NA
All Japonica	1512	19.60%	80.40%	0.00%	0.00%	NA
Aus	269	94.80%	5.20%	0.00%	0.00%	NA
Indica I	595	99.50%	0.30%	0.17%	0.00%	NA
Indica II	465	99.10%	0.90%	0.00%	0.00%	NA
Indica III	913	96.90%	3.10%	0.00%	0.00%	NA
Indica Intermediate	786	98.20%	1.80%	0.00%	0.00%	NA
Temperate Japonica	767	7.20%	92.80%	0.00%	0.00%	NA
Tropical Japonica	504	41.50%	58.50%	0.00%	0.00%	NA
Japonica Intermediate	241	13.30%	86.70%	0.00%	0.00%	NA
VI/Aromatic	96	14.60%	85.40%	0.00%	0.00%	NA
Intermediate	90	76.70%	22.20%	1.11%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0630338357	T -> C	LOC_Os06g50070.1	splice_region_variant ; LOW	silent_mutation	Average:75.143; most accessible tissue: Zhenshan97 flag leaf, score: 90.004	N	N	N	N
vg0630338357	T -> C	LOC_Os06g50070.1	3_prime_UTR_variant ; 333.0bp to feature; MODIFIER	silent_mutation	Average:75.143; most accessible tissue: Zhenshan97 flag leaf, score: 90.004	N	N	N	N
vg0630338357	T -> C	LOC_Os06g50060.1	upstream_gene_variant ; 1421.0bp to feature; MODIFIER	silent_mutation	Average:75.143; most accessible tissue: Zhenshan97 flag leaf, score: 90.004	N	N	N	N
vg0630338357	T -> C	LOC_Os06g50080.1	upstream_gene_variant ; 2089.0bp to feature; MODIFIER	silent_mutation	Average:75.143; most accessible tissue: Zhenshan97 flag leaf, score: 90.004	N	N	N	N
vg0630338357	T -> C	LOC_Os06g50050.1	downstream_gene_variant ; 2247.0bp to feature; MODIFIER	silent_mutation	Average:75.143; most accessible tissue: Zhenshan97 flag leaf, score: 90.004	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0630338357	T	C	-0.01	-0.02	-0.02	0.01	0.0	-0.01

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0630338357	NA	1.63E-06	mr1518	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0630338357	NA	1.46E-44	mr1563	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0630338357	NA	1.20E-06	mr1676	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0630338357	NA	5.49E-11	mr1055_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0630338357	6.87E-07	NA	mr1188_2	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251