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Detailed information for vg0215105940:

Variant ID: vg0215105940 (JBrowse)	Variation Type: SNP
Chromosome: chr02	Position: 15105940
Reference Allele: C	Alternative Allele: T
Primary Allele: C	Secondary Allele: T

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

ACACATTACGTCTTGAAGTTCGTGCTGCAGCGGGCTACAGATCATACACATTACATCTTGGAGTCCGTACTGCAACTGGCTACAGATCTATAGCCCGCTG[C/T]
TTTTCTCTCTTTTTAAAATGGTAAAATTGGTTATATAATATCGAAAGTATATTTATAGTTGGTTTGTACATGCTTTGAGCAGCTCGAACTCGATATGGAT

Reverse complement sequence

ATCCATATCGAGTTCGAGCTGCTCAAAGCATGTACAAACCAACTATAAATATACTTTCGATATTATATAACCAATTTTACCATTTTAAAAAGAGAGAAAA[G/A]
CAGCGGGCTATAGATCTGTAGCCAGTTGCAGTACGGACTCCAAGATGTAATGTGTATGATCTGTAGCCCGCTGCAGCACGAACTTCAAGACGTAATGTGT

Allele Frequencies:

Populations	Population Size	Frequency of C(primary allele)	Frequency of T(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	97.30%	1.60%	1.12%	0.00%	NA
All Indica	2759	95.50%	2.70%	1.81%	0.00%	NA
All Japonica	1512	100.00%	0.00%	0.00%	0.00%	NA
Aus	269	100.00%	0.00%	0.00%	0.00%	NA
Indica I	595	84.50%	8.70%	6.72%	0.00%	NA
Indica II	465	99.80%	0.00%	0.22%	0.00%	NA
Indica III	913	99.50%	0.30%	0.22%	0.00%	NA
Indica Intermediate	786	96.60%	2.50%	0.89%	0.00%	NA
Temperate Japonica	767	100.00%	0.00%	0.00%	0.00%	NA
Tropical Japonica	504	100.00%	0.00%	0.00%	0.00%	NA
Japonica Intermediate	241	100.00%	0.00%	0.00%	0.00%	NA
VI/Aromatic	96	100.00%	0.00%	0.00%	0.00%	NA
Intermediate	90	96.70%	0.00%	3.33%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0215105940	C -> T	LOC_Os02g25780.1	upstream_gene_variant ; 362.0bp to feature; MODIFIER	silent_mutation	Average:95.737; most accessible tissue: Callus, score: 99.112	N	N	N	N
vg0215105940	C -> T	LOC_Os02g25770.1	downstream_gene_variant ; 537.0bp to feature; MODIFIER	silent_mutation	Average:95.737; most accessible tissue: Callus, score: 99.112	N	N	N	N
vg0215105940	C -> T	LOC_Os02g25790.1	downstream_gene_variant ; 4962.0bp to feature; MODIFIER	silent_mutation	Average:95.737; most accessible tissue: Callus, score: 99.112	N	N	N	N
vg0215105940	C -> T	LOC_Os02g25770-LOC_Os02g25780	intergenic_region ; MODIFIER	silent_mutation	Average:95.737; most accessible tissue: Callus, score: 99.112	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0215105940	C	T	0.02	0.02	0.0	0.01	0.01	0.01

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0215105940	NA	6.51E-06	mr1414	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0215105940	NA	6.55E-09	mr1692	Ind_All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0215105940	NA	4.90E-06	mr1128_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0215105940	2.73E-06	2.12E-13	mr1855_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0215105940	NA	1.46E-06	mr1897_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0215105940	NA	6.65E-09	mr1914_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0215105940	NA	2.64E-07	mr1927_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251