Search for Variation information by Variation ID:

Please input a variation ID (e.g., vg0722097923).

Detailed information for vg0102692289:

Variant ID: vg0102692289 (JBrowse)	Variation Type: SNP
Chromosome: chr01	Position: 2692289
Reference Allele: C	Alternative Allele: T
Primary Allele: C	Secondary Allele: T

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

TTTGAACATTCGGATAAATATATGAAGTATTAAATATAAAAAAAATACTAATTATATAGATTATGTGTAAATTATGAGACGAATCTTTTAAGTCTAATTA[C/T]
AGTAAATATTTGCTTGTTAATGATAAATTAATTATGTTTAATAAATTTATCTCATAGCTTACTATCGGATTTTGTAATAAGTATTTTTATCAGTGCCGGA

Reverse complement sequence

TCCGGCACTGATAAAAATACTTATTACAAAATCCGATAGTAAGCTATGAGATAAATTTATTAAACATAATTAATTTATCATTAACAAGCAAATATTTACT[G/A]
TAATTAGACTTAAAAGATTCGTCTCATAATTTACACATAATCTATATAATTAGTATTTTTTTTATATTTAATACTTCATATATTTATCCGAATGTTCAAA

Allele Frequencies:

Populations	Population Size	Frequency of C(primary allele)	Frequency of T(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	89.30%	10.60%	0.13%	0.00%	NA
All Indica	2759	99.30%	0.70%	0.04%	0.00%	NA
All Japonica	1512	68.90%	30.80%	0.33%	0.00%	NA
Aus	269	100.00%	0.00%	0.00%	0.00%	NA
Indica I	595	98.80%	1.00%	0.17%	0.00%	NA
Indica II	465	99.10%	0.90%	0.00%	0.00%	NA
Indica III	913	99.90%	0.10%	0.00%	0.00%	NA
Indica Intermediate	786	99.00%	1.00%	0.00%	0.00%	NA
Temperate Japonica	767	49.50%	49.90%	0.52%	0.00%	NA
Tropical Japonica	504	98.60%	1.40%	0.00%	0.00%	NA
Japonica Intermediate	241	68.50%	31.10%	0.41%	0.00%	NA
VI/Aromatic	96	85.40%	14.60%	0.00%	0.00%	NA
Intermediate	90	95.60%	4.40%	0.00%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0102692289	C -> T	LOC_Os01g05640.1	upstream_gene_variant ; 103.0bp to feature; MODIFIER	silent_mutation	Average:87.131; most accessible tissue: Minghui63 root, score: 95.404	N	N	N	N
vg0102692289	C -> T	LOC_Os01g05630.1	downstream_gene_variant ; 4589.0bp to feature; MODIFIER	silent_mutation	Average:87.131; most accessible tissue: Minghui63 root, score: 95.404	N	N	N	N
vg0102692289	C -> T	LOC_Os01g05650.1	downstream_gene_variant ; 845.0bp to feature; MODIFIER	silent_mutation	Average:87.131; most accessible tissue: Minghui63 root, score: 95.404	N	N	N	N
vg0102692289	C -> T	LOC_Os01g05640-LOC_Os01g05650	intergenic_region ; MODIFIER	silent_mutation	Average:87.131; most accessible tissue: Minghui63 root, score: 95.404	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0102692289	C	T	0.03	-0.01	-0.03	0.01	-0.01	-0.02

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0102692289	NA	4.05E-07	mr1382	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	5.46E-06	mr1544	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	1.16E-07	NA	mr1916	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	5.69E-07	1.56E-10	mr1916	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	1.39E-06	mr1354_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	3.87E-10	mr1567_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	1.01E-06	mr1567_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	1.86E-06	mr1621_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	3.17E-13	mr1829_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	5.85E-06	mr1829_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	8.44E-18	mr1902_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0102692289	NA	2.21E-06	mr1902_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251