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Detailed information for vg1112708625:

Variant ID: vg1112708625 (JBrowse)Variation Type: SNP
Chromosome: chr11Position: 12708625
Reference Allele: TAlternative Allele: A
Primary Allele: TSecondary Allele: A

Inferred Ancestral Allele : T (evidence from allele frequency in Oryza rufipogon: T: 0.99, others allele: 0.00, population size: 313. )

Flanking Sequence (100 bp) in Reference Genome:


CAGAGTACAAACCAAATTACCTCCAATGAGACATGTAATGGTTGAGGAGGGGCATCGGATCTGAATCGATTCAGATGAGAGCTCTCCTTCCCTTAACCAT[T/A]
CGTTACTCATGATGGTGGTCAACTTCTTCACCGTCTCTTTAAGCATAGCTTTATCGAGAGGATCATTAGAGTTGACCTTGGTCGGTGGTCTCTTCTCGCA

Reverse complement sequence

TGCGAGAAGAGACCACCGACCAAGGTCAACTCTAATGATCCTCTCGATAAAGCTATGCTTAAAGAGACGGTGAAGAAGTTGACCACCATCATGAGTAACG[A/T]
ATGGTTAAGGGAAGGAGAGCTCTCATCTGAATCGATTCAGATCCGATGCCCCTCCTCAACCATTACATGTCTCATTGGAGGTAATTTGGTTTGTACTCTG

Allele Frequencies:

Populations Population SizeFrequency of T(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 93.50% 1.60% 1.40% 3.53% NA
All Indica  2759 94.90% 2.60% 2.10% 0.36% NA
All Japonica  1512 98.30% 0.10% 0.00% 1.65% NA
Aus  269 50.90% 0.00% 2.23% 46.84% NA
Indica I  595 84.00% 7.70% 8.24% 0.00% NA
Indica II  465 99.60% 0.00% 0.22% 0.22% NA
Indica III  913 98.60% 1.00% 0.11% 0.33% NA
Indica Intermediate  786 96.20% 2.20% 0.89% 0.76% NA
Temperate Japonica  767 99.90% 0.10% 0.00% 0.00% NA
Tropical Japonica  504 95.00% 0.00% 0.00% 4.96% NA
Japonica Intermediate  241 100.00% 0.00% 0.00% 0.00% NA
VI/Aromatic  96 95.80% 0.00% 0.00% 4.17% NA
Intermediate  90 93.30% 2.20% 2.22% 2.22% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg1112708625 T -> A LOC_Os11g22154.1 missense_variant ; p.Glu181Val; MODERATE nonsynonymous_codon ; E181V Average:44.611; most accessible tissue: Minghui63 flag leaf, score: 65.44 unknown unknown DELETERIOUS 0.01
vg1112708625 T -> DEL LOC_Os11g22154.1 N frameshift_variant Average:44.611; most accessible tissue: Minghui63 flag leaf, score: 65.44 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg1112708625 2.30E-07 2.15E-09 mr1097_2 Ind_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1112708625 6.23E-08 1.39E-08 mr1154_2 Ind_All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1112708625 NA 2.53E-06 mr1223_2 Ind_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251