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Detailed information for vg1012383116:

Variant ID: vg1012383116 (JBrowse)Variation Type: SNP
Chromosome: chr10Position: 12383116
Reference Allele: GAlternative Allele: T,A
Primary Allele: GSecondary Allele: A

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:


GAACTGAAGACTCTCCTATATCAAAAGTGATGGGAGAGTTAGGGAATCGGGACTTACCCTTGACCAGGAATCGATCCTGAGCCGCGAGGGCTTTGGATTC[G/T,A]
TCTCCCTGGTGATTCTCGGTTTCGCCGTGCCCGATGGGCGTTGGGGTCGTCATCCCCGATGCCGCTGCAGGTGAGTTCTCCAGAACCGTCACCCTTGCGG

Reverse complement sequence

CCGCAAGGGTGACGGTTCTGGAGAACTCACCTGCAGCGGCATCGGGGATGACGACCCCAACGCCCATCGGGCACGGCGAAACCGAGAATCACCAGGGAGA[C/A,T]
GAATCCAAAGCCCTCGCGGCTCAGGATCGATTCCTGGTCAAGGGTAAGTCCCGATTCCCTAACTCTCCCATCACTTTTGATATAGGAGAGTCTTCAGTTC

Allele Frequencies:

Populations Population SizeFrequency of G(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 80.90% 3.90% 2.20% 9.27% T: 3.83%
All Indica  2759 75.70% 6.50% 3.15% 8.16% T: 6.49%
All Japonica  1512 90.50% 0.00% 0.66% 8.86% NA
Aus  269 97.00% 0.00% 0.74% 2.23% NA
Indica I  595 87.70% 0.00% 3.70% 8.07% T: 0.50%
Indica II  465 83.00% 3.20% 3.44% 3.87% T: 6.45%
Indica III  913 65.60% 14.60% 1.86% 10.30% T: 7.67%
Indica Intermediate  786 74.00% 3.90% 4.07% 8.27% T: 9.67%
Temperate Japonica  767 98.00% 0.00% 0.26% 1.69% NA
Tropical Japonica  504 82.30% 0.00% 0.99% 16.67% NA
Japonica Intermediate  241 83.40% 0.00% 1.24% 15.35% NA
VI/Aromatic  96 34.40% 1.00% 3.12% 61.46% NA
Intermediate  90 77.80% 2.20% 2.22% 15.56% T: 2.22%

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg1012383116 G -> T LOC_Os10g24170.1 missense_variant ; p.Asp97Glu; MODERATE nonsynonymous_codon ; D97E Average:52.349; most accessible tissue: Zhenshan97 panicle, score: 67.02 unknown unknown TOLERATED 0.91
vg1012383116 G -> A LOC_Os10g24170.1 synonymous_variant ; p.Asp97Asp; LOW synonymous_codon Average:52.349; most accessible tissue: Zhenshan97 panicle, score: 67.02 N N N N
vg1012383116 G -> DEL LOC_Os10g24170.1 N frameshift_variant Average:52.349; most accessible tissue: Zhenshan97 panicle, score: 67.02 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg1012383116 2.40E-06 2.40E-06 mr1770 Ind_All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251