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Detailed information for vg1004372176:

Variant ID: vg1004372176 (JBrowse)Variation Type: SNP
Chromosome: chr10Position: 4372176
Reference Allele: GAlternative Allele: A
Primary Allele: GSecondary Allele: A

Inferred Ancestral Allele : G (evidence from allele frequency in Oryza rufipogon: G: 0.88, A: 0.12, others allele: 0.00, population size: 86. )

Flanking Sequence (100 bp) in Reference Genome:


ACGCGCAGCTGCAAGCTCAGCCGGTCGCTGCCCAAGCACACTCTCAGCCGCCTGGCCAAGTGTTACAAGCAATGGCAGAAGGGGCTTCGGCTCTGCAAGC[G/A]
CAACTTCAAGCTCTCCTTCAACAACTTAGGCCCTGTTTCTTTCAGCTTGGGATTATTATAATCAGATTATTGGGAGTAAGCTGAAAGAAACAGACAACTT

Reverse complement sequence

AAGTTGTCTGTTTCTTTCAGCTTACTCCCAATAATCTGATTATAATAATCCCAAGCTGAAAGAAACAGGGCCTAAGTTGTTGAAGGAGAGCTTGAAGTTG[C/T]
GCTTGCAGAGCCGAAGCCCCTTCTGCCATTGCTTGTAACACTTGGCCAGGCGGCTGAGAGTGTGCTTGGGCAGCGACCGGCTGAGCTTGCAGCTGCGCGT

Allele Frequencies:

Populations Population SizeFrequency of G(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 30.10% 16.20% 2.39% 51.35% NA
All Indica  2759 22.00% 16.50% 1.45% 60.09% NA
All Japonica  1512 50.50% 1.40% 4.56% 43.52% NA
Aus  269 1.10% 93.30% 0.74% 4.83% NA
Indica I  595 32.30% 42.40% 2.86% 22.52% NA
Indica II  465 21.10% 10.80% 0.65% 67.53% NA
Indica III  913 11.60% 3.40% 0.88% 84.12% NA
Indica Intermediate  786 26.70% 15.50% 1.53% 56.23% NA
Temperate Japonica  767 76.00% 0.30% 6.52% 17.21% NA
Tropical Japonica  504 16.90% 2.20% 2.18% 78.77% NA
Japonica Intermediate  241 39.80% 3.30% 3.32% 53.53% NA
VI/Aromatic  96 16.70% 20.80% 0.00% 62.50% NA
Intermediate  90 36.70% 18.90% 2.22% 42.22% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg1004372176 G -> A LOC_Os10g08070.1 missense_variant ; p.Ala218Thr; MODERATE nonsynonymous_codon ; A218T Average:46.834; most accessible tissue: Zhenshan97 flag leaf, score: 80.373 unknown unknown TOLERATED 0.06
vg1004372176 G -> DEL LOC_Os10g08070.1 N frameshift_variant Average:46.834; most accessible tissue: Zhenshan97 flag leaf, score: 80.373 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg1004372176 NA 9.59E-08 mr1087 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 NA 4.54E-07 mr1090 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 NA 5.96E-06 mr1094 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 NA 1.17E-06 mr1096 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 3.49E-06 3.49E-06 mr1234 Jap_All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 NA 4.85E-06 mr1577 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 NA 3.43E-09 mr1658 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg1004372176 NA 1.33E-06 mr1608_2 Ind_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251