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Detailed information for vg0816784758:

Variant ID: vg0816784758 (JBrowse)Variation Type: SNP
Chromosome: chr08Position: 16784758
Reference Allele: GAlternative Allele: A
Primary Allele: GSecondary Allele: A

Inferred Ancestral Allele : G (evidence from allele frequency in Oryza rufipogon: G: 0.98, A: 0.01, others allele: 0.00, population size: 107. )

Flanking Sequence (100 bp) in Reference Genome:


CGCCTTCTCTCGGTGTAGGACGTCGAAGGCAGAGGTTCCGGAGACCTGCTCTCCCGATCGCCGGTGCACGCCGGCGAGTGGGATAGAGTAGTCTACGAGC[G/A]
ACGGCGCAGCACAGAGTAGGAGGCAAACCCTAGATTGATTTCGCATATGTTCATCAAGACGATAAGTCGCGCTGCGCAAGGCTGAGGAGCCAATTTTGCG

Reverse complement sequence

CGCAAAATTGGCTCCTCAGCCTTGCGCAGCGCGACTTATCGTCTTGATGAACATATGCGAAATCAATCTAGGGTTTGCCTCCTACTCTGTGCTGCGCCGT[C/T]
GCTCGTAGACTACTCTATCCCACTCGCCGGCGTGCACCGGCGATCGGGAGAGCAGGTCTCCGGAACCTCTGCCTTCGACGTCCTACACCGAGAGAAGGCG

Allele Frequencies:

Populations Population SizeFrequency of G(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 63.40% 10.90% 0.93% 24.80% NA
All Indica  2759 43.50% 13.50% 1.56% 41.43% NA
All Japonica  1512 98.90% 0.10% 0.07% 0.93% NA
Aus  269 47.20% 50.90% 0.00% 1.86% NA
Indica I  595 58.80% 29.20% 0.50% 11.43% NA
Indica II  465 40.40% 4.70% 2.15% 52.69% NA
Indica III  913 29.50% 9.10% 1.86% 59.58% NA
Indica Intermediate  786 50.10% 11.80% 1.65% 36.39% NA
Temperate Japonica  767 99.20% 0.10% 0.00% 0.65% NA
Tropical Japonica  504 98.40% 0.00% 0.00% 1.59% NA
Japonica Intermediate  241 99.20% 0.00% 0.41% 0.41% NA
VI/Aromatic  96 96.90% 2.10% 0.00% 1.04% NA
Intermediate  90 85.60% 4.40% 0.00% 10.00% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg0816784758 G -> A LOC_Os08g27500.1 missense_variant ; p.Ser51Leu; MODERATE nonsynonymous_codon ; S51L Average:32.073; most accessible tissue: Zhenshan97 flag leaf, score: 79.006 unknown unknown DELETERIOUS 0.03
vg0816784758 G -> DEL LOC_Os08g27500.1 N frameshift_variant Average:32.073; most accessible tissue: Zhenshan97 flag leaf, score: 79.006 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg0816784758 NA 2.51E-08 mr1857 All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0816784758 NA 4.60E-06 mr1528_2 All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251