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Detailed information for vg0804903477:

Variant ID: vg0804903477 (JBrowse)	Variation Type: SNP
Chromosome: chr08	Position: 4903477
Reference Allele: C	Alternative Allele: T
Primary Allele: C	Secondary Allele: T

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

CAGGGTTGGGTTTTGTTACAAAGGTTGAATGAAAATTTGGATATTTGTAACACGTTTTTCAAATTGCTAAATGGTACATTCAGTGCGAAAATTTTCTATA[C/T]
GGAAGTTGCTCTAAAATATTAGATAAATATATTTTTTAAGTTTATAATAATTAAAACCTAATTAATTATACATTAATACTACCTCGTTTTTATGTAAAAC

Reverse complement sequence

GTTTTACATAAAAACGAGGTAGTATTAATGTATAATTAATTAGGTTTTAATTATTATAAACTTAAAAAATATATTTATCTAATATTTTAGAGCAACTTCC[G/A]
TATAGAAAATTTTCGCACTGAATGTACCATTTAGCAATTTGAAAAACGTGTTACAAATATCCAAATTTTCATTCAACCTTTGTAACAAAACCCAACCCTG

Allele Frequencies:

Populations	Population Size	Frequency of C(primary allele)	Frequency of T(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	71.20%	8.70%	3.00%	17.03%	NA
All Indica	2759	75.60%	14.40%	0.51%	9.46%	NA
All Japonica	1512	57.40%	0.20%	7.87%	34.52%	NA
Aus	269	96.70%	0.40%	0.74%	2.23%	NA
Indica I	595	91.40%	3.20%	0.17%	5.21%	NA
Indica II	465	60.40%	7.50%	1.08%	30.97%	NA
Indica III	913	73.80%	25.80%	0.22%	0.11%	NA
Indica Intermediate	786	74.80%	13.60%	0.76%	10.81%	NA
Temperate Japonica	767	87.10%	0.00%	1.69%	11.21%	NA
Tropical Japonica	504	19.60%	0.20%	12.50%	67.66%	NA
Japonica Intermediate	241	41.90%	0.80%	17.84%	39.42%	NA
VI/Aromatic	96	92.70%	3.10%	3.12%	1.04%	NA
Intermediate	90	68.90%	10.00%	4.44%	16.67%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0804903477	C -> T	LOC_Os08g08500.1	upstream_gene_variant ; 3218.0bp to feature; MODIFIER	silent_mutation	Average:77.213; most accessible tissue: Callus, score: 91.041	N	N	N	N
vg0804903477	C -> T	LOC_Os08g08510.1	upstream_gene_variant ; 3325.0bp to feature; MODIFIER	silent_mutation	Average:77.213; most accessible tissue: Callus, score: 91.041	N	N	N	N
vg0804903477	C -> T	LOC_Os08g08500-LOC_Os08g08510	intergenic_region ; MODIFIER	silent_mutation	Average:77.213; most accessible tissue: Callus, score: 91.041	N	N	N	N
vg0804903477	C -> DEL	N	N	silent_mutation	Average:77.213; most accessible tissue: Callus, score: 91.041	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0804903477	C	T	-0.02	0.0	-0.01	-0.02	-0.02	-0.01

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0804903477	4.36E-07	4.36E-07	mr1281_2	Ind_All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251