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Detailed information for vg0526981252:

Variant ID: vg0526981252 (JBrowse)	Variation Type: SNP
Chromosome: chr05	Position: 26981252
Reference Allele: G	Alternative Allele: A
Primary Allele: G	Secondary Allele: A

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

CATCCAGCTACACTGGACTCGGCAGCCTGGGTTGGAACCCATGTCCCGCACACGAAAACGAAGCGGTCCATTAGCGCATAATTAATTAAGTACTTCCTTC[G/A]
TTTCACAATATAAGTTATTTTAGCATTTTTCACATTCATATTGATGCTAATGAATTTAGACATATATATCTATCTAGATTCATTAATATCAATATGGATG

Reverse complement sequence

CATCCATATTGATATTAATGAATCTAGATAGATATATATGTCTAAATTCATTAGCATCAATATGAATGTGAAAAATGCTAAAATAACTTATATTGTGAAA[C/T]
GAAGGAAGTACTTAATTAATTATGCGCTAATGGACCGCTTCGTTTTCGTGTGCGGGACATGGGTTCCAACCCAGGCTGCCGAGTCCAGTGTAGCTGGATG

Allele Frequencies:

Populations	Population Size	Frequency of G(primary allele)	Frequency of A(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	87.20%	11.40%	1.40%	0.00%	NA
All Indica	2759	78.80%	19.00%	2.25%	0.00%	NA
All Japonica	1512	99.50%	0.50%	0.07%	0.00%	NA
Aus	269	100.00%	0.00%	0.00%	0.00%	NA
Indica I	595	67.40%	28.70%	3.87%	0.00%	NA
Indica II	465	70.10%	28.60%	1.29%	0.00%	NA
Indica III	913	92.10%	7.80%	0.11%	0.00%	NA
Indica Intermediate	786	77.10%	18.80%	4.07%	0.00%	NA
Temperate Japonica	767	99.20%	0.70%	0.13%	0.00%	NA
Tropical Japonica	504	99.60%	0.40%	0.00%	0.00%	NA
Japonica Intermediate	241	100.00%	0.00%	0.00%	0.00%	NA
VI/Aromatic	96	97.90%	2.10%	0.00%	0.00%	NA
Intermediate	90	87.80%	8.90%	3.33%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0526981252	G -> A	LOC_Os05g46600-LOC_Os05g46610	intergenic_region ; MODIFIER	silent_mutation	Average:73.8; most accessible tissue: Zhenshan97 flower, score: 82.111	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0526981252	G	A	-0.03	0.0	0.0	0.0	0.0	0.0

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0526981252	1.86E-06	1.86E-06	mr1412	Ind_All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0526981252	NA	5.20E-06	mr1782	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251