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Detailed information for vg0317097954:

Variant ID: vg0317097954 (JBrowse)	Variation Type: SNP
Chromosome: chr03	Position: 17097954
Reference Allele: A	Alternative Allele: G
Primary Allele: G	Secondary Allele: A

Inferred Ancestral Allele : G (evidence from allele frequency in Oryza rufipogon: G: 0.97, A: 0.03, others allele: 0.00, population size: 116. )

Flanking Sequence (100 bp) in Reference Genome:

TCGTAAACACAGAGAGAATCAATAAAGTCGTCATCCACTTTAAGAGTTCTTCGATTTGTGATTCATCGGGTTTCGACGGTCTAACCGGCGATCTACCGGC[A/G]
GTCAGACCGGCGGTAAGCGGCGGTCAGACCAAAGGGAGCACGGCAGTCAGACCTGTGGTAGCGACAGCGAGCGGCAGCTGATCTCAGCGGTCAGACCGGA

Reverse complement sequence

TCCGGTCTGACCGCTGAGATCAGCTGCCGCTCGCTGTCGCTACCACAGGTCTGACTGCCGTGCTCCCTTTGGTCTGACCGCCGCTTACCGCCGGTCTGAC[T/C]
GCCGGTAGATCGCCGGTTAGACCGTCGAAACCCGATGAATCACAAATCGAAGAACTCTTAAAGTGGATGACGACTTTATTGATTCTCTCTGTGTTTACGA

Allele Frequencies:

Populations	Population Size	Frequency of G(primary allele)	Frequency of A(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	62.00%	37.50%	0.36%	0.11%	NA
All Indica	2759	90.00%	9.50%	0.36%	0.14%	NA
All Japonica	1512	4.20%	95.50%	0.26%	0.07%	NA
Aus	269	94.40%	5.60%	0.00%	0.00%	NA
Indica I	595	97.50%	1.00%	1.18%	0.34%	NA
Indica II	465	88.20%	11.60%	0.00%	0.22%	NA
Indica III	913	84.10%	15.80%	0.00%	0.11%	NA
Indica Intermediate	786	92.20%	7.40%	0.38%	0.00%	NA
Temperate Japonica	767	0.80%	98.70%	0.52%	0.00%	NA
Tropical Japonica	504	10.70%	89.30%	0.00%	0.00%	NA
Japonica Intermediate	241	1.20%	98.30%	0.00%	0.41%	NA
VI/Aromatic	96	83.30%	16.70%	0.00%	0.00%	NA
Intermediate	90	56.70%	40.00%	3.33%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0317097954	A -> DEL	N	N	silent_mutation	Average:73.981; most accessible tissue: Zhenshan97 flag leaf, score: 91.812	N	N	N	N
vg0317097954	A -> G	LOC_Os03g29980.2	downstream_gene_variant ; 1684.0bp to feature; MODIFIER	silent_mutation	Average:73.981; most accessible tissue: Zhenshan97 flag leaf, score: 91.812	N	N	N	N
vg0317097954	A -> G	LOC_Os03g29980-LOC_Os03g29990	intergenic_region ; MODIFIER	silent_mutation	Average:73.981; most accessible tissue: Zhenshan97 flag leaf, score: 91.812	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0317097954	A	G	0.02	0.02	0.01	0.01	0.0	-0.01

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0317097954	NA	1.70E-06	mr1063_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	2.53E-06	mr1252_2	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	5.46E-09	mr1299_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	1.41E-11	mr1377_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	4.34E-06	4.34E-06	mr1377_2	Jap_All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	3.88E-06	mr1391_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	1.42E-18	mr1637_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	8.15E-08	mr1700_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	1.18E-06	mr1727_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	5.88E-08	mr1837_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0317097954	NA	1.84E-18	mr1945_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251