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Detailed information for vg0112449854:

Variant ID: vg0112449854 (JBrowse)Variation Type: SNP
Chromosome: chr01Position: 12449854
Reference Allele: GAlternative Allele: A
Primary Allele: GSecondary Allele: A

Inferred Ancestral Allele : G (evidence from allele frequency in Oryza rufipogon: G: 0.97, A: 0.02, others allele: 0.00, population size: 81. )

Flanking Sequence (100 bp) in Reference Genome:


AAATTGATAATAGAGTACAAATATTACTCTAATTAATAAGCGAATAAACTGTCATTATAGAGGTAGATAGTTCCTCTCAATCAATAAAGATCTAAGCAGC[G/A]
GAAAATAAATAAACGGCGCAGACGGCTCCACTCCACAGGCAGCTTGACCAAGGCTACACCTAATCCTCCACACCATCAGCCTCATTGTAGAACTCTTCCT

Reverse complement sequence

AGGAAGAGTTCTACAATGAGGCTGATGGTGTGGAGGATTAGGTGTAGCCTTGGTCAAGCTGCCTGTGGAGTGGAGCCGTCTGCGCCGTTTATTTATTTTC[C/T]
GCTGCTTAGATCTTTATTGATTGAGAGGAACTATCTACCTCTATAATGACAGTTTATTCGCTTATTAATTAGAGTAATATTTGTACTCTATTATCAATTT

Allele Frequencies:

Populations Population SizeFrequency of G(primary allele) Frequency of A(secondary allele) Frequency of N Frequency of DEL Frequency of others Allele
All  4726 29.70% 2.00% 12.38% 55.97% NA
All Indica  2759 4.70% 0.00% 13.19% 82.09% NA
All Japonica  1512 76.90% 6.00% 5.69% 11.38% NA
Aus  269 1.10% 0.00% 45.72% 53.16% NA
Indica I  595 3.20% 0.00% 1.68% 95.13% NA
Indica II  465 5.80% 0.00% 4.73% 89.46% NA
Indica III  913 4.80% 0.00% 23.11% 72.07% NA
Indica Intermediate  786 5.00% 0.10% 15.39% 79.52% NA
Temperate Japonica  767 79.00% 11.90% 3.78% 5.35% NA
Tropical Japonica  504 81.00% 0.00% 5.56% 13.49% NA
Japonica Intermediate  241 61.80% 0.00% 12.03% 26.14% NA
VI/Aromatic  96 68.80% 0.00% 0.00% 31.25% NA
Intermediate  90 46.70% 1.10% 13.33% 38.89% NA

Allele Effect:

Var ID Var Locus snpEff Annotation CooVar Annotation Chromatin Accessibility Score PolyPhen-2 Effect PolyPhen-2 Score SIFT Effect SIFT Score
vg0112449854 G -> A LOC_Os01g22150.1 upstream_gene_variant ; 3704.0bp to feature; MODIFIER silent_mutation Average:6.05; most accessible tissue: Minghui63 young leaf, score: 9.976 N N N N
vg0112449854 G -> A LOC_Os01g22150-LOC_Os01g22170 intergenic_region ; MODIFIER silent_mutation Average:6.05; most accessible tissue: Minghui63 young leaf, score: 9.976 N N N N
vg0112449854 G -> DEL N N silent_mutation Average:6.05; most accessible tissue: Minghui63 young leaf, score: 9.976 N N N N

Putative Genotype-Phenotype Associations:

Var ID LMM P-value LR P-value Trait Subpopulation Is leadSNP Publication
vg0112449854 4.72E-07 NA mr1648 All YES Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0112449854 NA 3.63E-09 mr1648 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0112449854 NA 8.54E-07 mr1164_2 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0112449854 NA 1.38E-09 mr1709_2 Jap_All Not Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251