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Detailed information for vg0706319441:

Variant ID: vg0706319441 (JBrowse)	Variation Type: SNP
Chromosome: chr07	Position: 6319441
Reference Allele: C	Alternative Allele: T
Primary Allele: T	Secondary Allele: C

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

AAATATTTAAAATAATACAATAAATAATTTGTGACACATAAATAGGTCTTATGACATAGTAAATATTGTCACTGGATGACACTAGACTAGCTATATGACA[C/T]
TTATTGTGACACACAACTTTTTATTGTCATTAAGTTAAAATGCTTCAAATAAAATGTCATAAATTAGATGATATAGTGACATTATAACCTGTGTCATATA

Reverse complement sequence

TATATGACACAGGTTATAATGTCACTATATCATCTAATTTATGACATTTTATTTGAAGCATTTTAACTTAATGACAATAAAAAGTTGTGTGTCACAATAA[G/A]
TGTCATATAGCTAGTCTAGTGTCATCCAGTGACAATATTTACTATGTCATAAGACCTATTTATGTGTCACAAATTATTTATTGTATTATTTTAAATATTT

Allele Frequencies:

Populations	Population Size	Frequency of T(primary allele)	Frequency of C(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	73.10%	11.60%	2.88%	12.34%	NA
All Indica	2759	92.30%	1.60%	2.21%	3.91%	NA
All Japonica	1512	45.70%	32.30%	3.70%	18.25%	NA
Aus	269	23.80%	0.40%	5.58%	70.26%	NA
Indica I	595	90.30%	2.70%	4.20%	2.86%	NA
Indica II	465	94.40%	3.40%	2.15%	0.00%	NA
Indica III	913	95.80%	0.30%	0.22%	3.61%	NA
Indica Intermediate	786	88.40%	1.10%	3.05%	7.38%	NA
Temperate Japonica	767	21.40%	47.60%	4.95%	26.08%	NA
Tropical Japonica	504	79.60%	7.30%	1.59%	11.51%	NA
Japonica Intermediate	241	52.30%	36.10%	4.15%	7.47%	NA
VI/Aromatic	96	96.90%	1.00%	0.00%	2.08%	NA
Intermediate	90	70.00%	16.70%	4.44%	8.89%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0706319441	C -> DEL	N	N	silent_mutation	Average:86.007; most accessible tissue: Callus, score: 97.047	N	N	N	N
vg0706319441	C -> T	LOC_Os07g11490.1	upstream_gene_variant ; 1384.0bp to feature; MODIFIER	silent_mutation	Average:86.007; most accessible tissue: Callus, score: 97.047	N	N	N	N
vg0706319441	C -> T	LOC_Os07g11490.2	upstream_gene_variant ; 1382.0bp to feature; MODIFIER	silent_mutation	Average:86.007; most accessible tissue: Callus, score: 97.047	N	N	N	N
vg0706319441	C -> T	LOC_Os07g11490.3	upstream_gene_variant ; 2204.0bp to feature; MODIFIER	silent_mutation	Average:86.007; most accessible tissue: Callus, score: 97.047	N	N	N	N
vg0706319441	C -> T	LOC_Os07g11490-LOC_Os07g11500	intergenic_region ; MODIFIER	silent_mutation	Average:86.007; most accessible tissue: Callus, score: 97.047	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0706319441	C	T	-0.08	-0.04	-0.04	-0.06	-0.07	-0.06

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0706319441	NA	4.26E-06	mr1097	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0706319441	3.50E-07	NA	mr1115	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0706319441	NA	3.10E-06	mr1149	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0706319441	NA	3.15E-08	mr1252	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0706319441	4.02E-06	NA	mr1611	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0706319441	NA	1.60E-12	mr1626	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251