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Detailed information for vg0607540736:

Variant ID: vg0607540736 (JBrowse)	Variation Type: SNP
Chromosome: chr06	Position: 7540736
Reference Allele: G	Alternative Allele: A
Primary Allele: G	Secondary Allele: A

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

GTTGCTTAGTTAGAGTTCACCCTCACCAAGCCTAGCAACTTAGGTTAGATTTGATTAGGTGTTATTTGTTTTTAAATCGCCTATTCACCCTCCTCTAGTC[G/A]
ACATCTCGATCCTACAGTGGGGCCATGTGGGCCCCACATGTCAGCCTCACTCCTCTCTTCTTCCCTCTCCCTTCTCTCTCTTCTTCCCTTTCCCCTCTCT

Reverse complement sequence

AGAGAGGGGAAAGGGAAGAAGAGAGAGAAGGGAGAGGGAAGAAGAGAGGAGTGAGGCTGACATGTGGGGCCCACATGGCCCCACTGTAGGATCGAGATGT[C/T]
GACTAGAGGAGGGTGAATAGGCGATTTAAAAACAAATAACACCTAATCAAATCTAACCTAAGTTGCTAGGCTTGGTGAGGGTGAACTCTAACTAAGCAAC

Allele Frequencies:

Populations	Population Size	Frequency of G(primary allele)	Frequency of A(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	96.50%	3.20%	0.28%	0.00%	NA
All Indica	2759	95.00%	4.60%	0.47%	0.00%	NA
All Japonica	1512	99.70%	0.30%	0.00%	0.00%	NA
Aus	269	93.30%	6.70%	0.00%	0.00%	NA
Indica I	595	85.90%	13.10%	1.01%	0.00%	NA
Indica II	465	99.40%	0.60%	0.00%	0.00%	NA
Indica III	913	98.90%	0.90%	0.22%	0.00%	NA
Indica Intermediate	786	94.70%	4.70%	0.64%	0.00%	NA
Temperate Japonica	767	99.50%	0.50%	0.00%	0.00%	NA
Tropical Japonica	504	100.00%	0.00%	0.00%	0.00%	NA
Japonica Intermediate	241	100.00%	0.00%	0.00%	0.00%	NA
VI/Aromatic	96	97.90%	2.10%	0.00%	0.00%	NA
Intermediate	90	97.80%	2.20%	0.00%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0607540736	G -> A	LOC_Os06g13610.1	upstream_gene_variant ; 38.0bp to feature; MODIFIER	silent_mutation	Average:77.952; most accessible tissue: Minghui63 young leaf, score: 87.965	N	N	N	N
vg0607540736	G -> A	LOC_Os06g13620.1	upstream_gene_variant ; 3970.0bp to feature; MODIFIER	silent_mutation	Average:77.952; most accessible tissue: Minghui63 young leaf, score: 87.965	N	N	N	N
vg0607540736	G -> A	LOC_Os06g13600-LOC_Os06g13610	intergenic_region ; MODIFIER	silent_mutation	Average:77.952; most accessible tissue: Minghui63 young leaf, score: 87.965	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0607540736	G	A	0.02	0.0	-0.01	0.0	0.0	0.0

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0607540736	NA	4.32E-07	mr1728	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0607540736	2.68E-06	NA	mr1128_2	Ind_All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0607540736	NA	3.52E-06	mr1405_2	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0607540736	NA	2.84E-07	mr1547_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0607540736	NA	1.52E-06	mr1547_2	Ind_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0607540736	NA	5.31E-06	mr1597_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0607540736	NA	6.72E-07	mr1863_2	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251