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Detailed information for vg0308202313:

Variant ID: vg0308202313 (JBrowse)	Variation Type: SNP
Chromosome: chr03	Position: 8202313
Reference Allele: A	Alternative Allele: T
Primary Allele: T	Secondary Allele: A

Inferred Ancestral Allele: Not determined.

Flanking Sequence (100 bp) in Reference Genome:

TACGTGATGGTTCGGTGGCGCACACGGCGTGGGTGGGGGGGGGGGGGGGGTGAGCAAACGCCACGGCCACGCCATGCCGCATCTGATCTCTCTCCCGTCC[A/T]
CCCTTTTGCTTCCGCTGCTGCATGTGCCCTTGGCATTGGCCGCACGGGCTCACAGCTAGGACGGACCAGTAAACAAAAGGTGCCGGTGTGACCGACCGAC

Reverse complement sequence

GTCGGTCGGTCACACCGGCACCTTTTGTTTACTGGTCCGTCCTAGCTGTGAGCCCGTGCGGCCAATGCCAAGGGCACATGCAGCAGCGGAAGCAAAAGGG[T/A]
GGACGGGAGAGAGATCAGATGCGGCATGGCGTGGCCGTGGCGTTTGCTCACCCCCCCCCCCCCCCCACCCACGCCGTGTGCGCCACCGAACCATCACGTA

Allele Frequencies:

Populations	Population Size	Frequency of T(primary allele)	Frequency of A(secondary allele)	Frequency of N	Frequency of DEL	Frequency of others Allele
All	4726	93.30%	6.70%	0.06%	0.00%	NA
All Indica	2759	99.90%	0.10%	0.00%	0.00%	NA
All Japonica	1512	79.60%	20.20%	0.20%	0.00%	NA
Aus	269	100.00%	0.00%	0.00%	0.00%	NA
Indica I	595	100.00%	0.00%	0.00%	0.00%	NA
Indica II	465	99.60%	0.40%	0.00%	0.00%	NA
Indica III	913	100.00%	0.00%	0.00%	0.00%	NA
Indica Intermediate	786	99.90%	0.10%	0.00%	0.00%	NA
Temperate Japonica	767	61.30%	38.30%	0.39%	0.00%	NA
Tropical Japonica	504	99.80%	0.20%	0.00%	0.00%	NA
Japonica Intermediate	241	95.90%	4.10%	0.00%	0.00%	NA
VI/Aromatic	96	100.00%	0.00%	0.00%	0.00%	NA
Intermediate	90	92.20%	7.80%	0.00%	0.00%	NA

Allele Effect:

Var ID	Var	Locus	snpEff Annotation	CooVar Annotation	Chromatin Accessibility Score	PolyPhen-2 Effect	PolyPhen-2 Score	SIFT Effect	SIFT Score
vg0308202313	A -> T	LOC_Os03g15020.1	upstream_gene_variant ; 145.0bp to feature; MODIFIER	silent_mutation	Average:97.593; most accessible tissue: Zhenshan97 panicle, score: 99.622	N	N	N	N
vg0308202313	A -> T	LOC_Os03g15020.2	upstream_gene_variant ; 145.0bp to feature; MODIFIER	silent_mutation	Average:97.593; most accessible tissue: Zhenshan97 panicle, score: 99.622	N	N	N	N
vg0308202313	A -> T	LOC_Os03g15020.3	upstream_gene_variant ; 145.0bp to feature; MODIFIER	silent_mutation	Average:97.593; most accessible tissue: Zhenshan97 panicle, score: 99.622	N	N	N	N
vg0308202313	A -> T	LOC_Os03g15020-LOC_Os03g15033	intergenic_region ; MODIFIER	silent_mutation	Average:97.593; most accessible tissue: Zhenshan97 panicle, score: 99.622	N	N	N	N

Effects Predicted by Deep Convolutional Neural Networks

For each variant, we constructed two sequences that contain the variation site and the sequence around it, differing only in the variation site. We then used Basenji to predict the chromatin accessibility of each tissue for the two sequences, respectively, and scored the effect of the variant by comparing the changes in chromatin accessibility corresponding to the two genotypes in the 1 kb region around the variation site. The effect score was defined as the logarithmic ratio of the predicted chromatin accessibility of the alternative genotype to the value of the reference genotype.

Var ID	Ref	Alt	Root (RT)	Young Leaf (YL)	Flag Leaf (FL)	Young Panicle (YP)	Lemma & Palea (LP)	Stamen & Pistil (SP)
vg0308202313	A	T	-0.01	-0.02	-0.03	-0.07	-0.02	0.03

Putative Genotype-Phenotype Associations:

Var ID	LMM P-value	LR P-value	Trait	Subpopulation	Is leadSNP	Publication
vg0308202313	NA	1.51E-07	mr1026	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	3.20E-06	mr1171	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	5.77E-06	NA	mr1585	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	3.93E-07	mr1585	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	6.13E-07	mr1627	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	2.55E-15	mr1712	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	1.80E-06	mr1712	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	1.64E-06	NA	mr1779	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	7.86E-07	7.86E-07	mr1779	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	9.12E-09	mr1946	All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	9.41E-11	mr1977	All	YES	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251
vg0308202313	NA	7.87E-07	mr1977	Jap_All	Not	Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism, Nat Genet, 46(7):714-21, PMID:24908251